Drug induced accumulation of phospholipids (phospholipidosis) is associated with clinical toxicities. Cell‐based assays can help to evaluate the phospholipidosis risk of a drug at an early stage of preclinical development and may reduce animal testing. The instaCELL Phospholipidosis Assay Kits includes pre‐qualified assay ready HepG2 cells which are ready to use like a reagent. The kit also contains positive and negative controls and a fluorescent dye to detect the accumulation phospholipids.