PRC ‐ Patch Ready Cells (Voltage Gated Ion Channels)

Patch Ready Cells are pre‐qualified aliquots of cryopreserved cells which can be used in patch clamp assays without prior cultivation. The set of cell lines expresses pharmaceutically relevant ion channels including the six cardiac channels of the CiPA panel. The ion channel cell lines have been developed by b’sys, Switzerland, despite one. CHO‐CaV1.2 was constructed by Steinbeis-Innovationszentrum Zellkulturtechnik; Germany in cooperation with the NMI TT Pharmaservices, Germany by using the Igami Technology.

Assay Ready Cells



CHO‐Kir2.1 Patch Ready Cells (RE301)

inward‐rectifier potassium channel Kir2.1 (KCNJ2)
5 million cryopreserved cells/vial
recovery buffer, patch buffer

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CHO‐Kv4.3/KChIP2 Patch Ready Cells (RE302)

voltage‐gated potassium channel Kv4.3 (KCND3) & KChIP2
5 million cryopreserved cells/vial
recovery buffer, patch buffer

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CHO‐KvLQT1/mink Patch Ready Cells (RE303)

voltage‐gated potassium channel Kv7.1 (KCNQ1 ) & minK
5 million cryopreserved cells/vial
recovery buffer, patch buffer

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CHO‐hERG‐DUO Patch Ready Cells (RE304)

voltage‐gated potassium channel Kv11.1 (KCNH2)
5 million cryopreserved cells/vial
recovery buffer, patch buffer

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CHO‐NaV1.5‐DUO Patch Ready Cells (RE305)

voltage‐gated sodium channel 1.5 (SNC5A)
5 million cryopreserved cells/vial
recovery buffer, patch buffer

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CHO‐CaV1.2 Patch Ready Cells (RE306)

voltage‐gated calcium channel 1.2 (CACN‐A1C, ‐B2, ‐A2D)
5 million cells/vial
recovery buffer, patch buffer

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HEK‐NaV1.4 Patch Ready Cells (RE307)

voltage‐gated sodium channel 1.4 (SNC4)
5 million cryopreserved cells/vial
recovery buffer, patch buffer

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